Journal: Scientific Reports
Article Title: Decoding microglia responses to psychosocial stress reveals blood-brain barrier breakdown that may drive stress susceptibility
doi: 10.1038/s41598-018-28737-8
Figure Lengend Snippet: Microarray analysis of microglial gene expression in HC, CSD-S, and CSD-R mice shows a major effect in susceptible microglia. ( a ) Heat map results from unsupervised clustering for all differentially expressed genes reveals treatment grouping (One-way ANOVA; false discovery rate (FDR) q < 0.05). ( b ) Comparison of up- and down-regulated genes with ≥1.5x change in gene expression in the two defeated groups compared to HC.
Article Snippet: Normalized data sets were compared in Partek by ANOVA with false discovery rate (FDR) correction ( q < 0.05) to assess differential transcript expression across behavioral phenotypes.
Techniques: Microarray, Gene Expression, Comparison